A group of scientists from the Max Planck Institute in Germany conducted experiments on mice, testing a cocktail of two drugs with rejuvenating properties. The results showed that the lifespan of the animals increased by 30 percent, and there was also an improvement in overall health. The results of the study were published in the journal Nature Aging. The study used the drugs rapamycin and trametinib, which are used to treat various forms of cancer. Rapamycin has already been shown to extend lifespan in animal clinical trials, and trametinib has previously shown similar effects in fruit flies. However, its effects in larger animals were questionable. The scientists studied how each drug affected the lifespan of mice, both individually and in combination. Rapamycin extended the lifespan of mice by 17 to 18 percent, while trametinib added another 7 to 16 percent. Together, their effect was significantly more powerful, increasing lifespan by 26 to 35 percent. Importantly, the extra lifespan the animals received did not come with any deterioration in health. The combination treatment slowed the growth of liver and spleen tumors and reduced chronic inflammation in various organs, including the brain and kidneys. The treated mice were more active in old age and weighed less, as well as had more stable heart function compared to the control group. While the study’s results are encouraging, scientists caution against expecting a significant increase in human life expectancy. The focus is on improving quality of life in old age. Study co-author and geneticist Linda Partridge emphasizes that the drugs could help people stay healthy and active in old age. Human trials are expected to begin in the coming years. The post Scientists Increase Mice Lifespan By 30% With Anti-Aging Cocktail appeared first on Anomalien.com.