Upending decades-old guidance, the Centers for Disease Control and Prevention's vaccine advisory committee voted to no longer issue a blanket recommendation that all newborns receive a hepatitis B vaccine at birth. Throughout the meeting, many panelists made misleading claims about the vaccine. Here, we address claims about the vaccine's effectiveness and safety, and other countries' vaccination policies. The hepatitis B vaccine, which is typically given in a three-dose series, is highly effective in preventing disease and has a strong safety record. As the Children's Hospital of Philadelphia explains, there are no known serious side effects other than anaphylaxis, or a life-threatening allergic reaction, which is very rare and can be treated.