phys.org
Novel insights into antibody aggregation expected to open up new avenues for research and therapeutic applications
Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development. However‚ their light chains—parts of the antibody that contribute to recognizing and binding to specific antigens—misfold and aggregate‚ leading to amyloidosis‚ a condition that brings about complications and tissue dysfunction in the body.
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