Introducing HORNET,  a novel RNA structure visualization method that correlates sequence and 3D topology
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Introducing HORNET, a novel RNA structure visualization method that correlates sequence and 3D topology

National Cancer Institute researchers have developed a method called HORNET for characterizing 3D topological structures of large and flexible RNA molecules. Scientists used atomic force microscopy (AFM) with deep neural networks and unsupervised machine learning to capture individual conformers under physiological conditions.