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Orange cats come with genetic twist: X-linked mutation points to new mechanism for coloring
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phys.org

Orange cats come with genetic twist: X-linked mutation points to new mechanism for coloring

From Tama, Japan's most famous stationmaster calico cat, to the lasagna-loving, ginger Garfield, cats with orange fur are both cultural icons and beloved pets. But their distinctive color comes with a genetic twist—most orange tabbies are male, while calicos and tortoiseshells are nearly always female. This pattern points to an unknown "orange gene" on the X chromosome, but identifying this gene has eluded scientists for decades.
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