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The Lighter Side
The Lighter Side
4 w

Smelling your own farts might be good for your brain, science says
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Smelling your own farts might be good for your brain, science says

BY THE OPTIMIST DAILY EDITORIAL TEAM It’s long been the butt of jokes, but the science is catching up: fart gas might actually be good for you. Researchers at Johns Hopkins Medicine say that hydrogen sulfide, the chemical behind that telltale rotten-egg smell, might help protect the aging brain from cognitive decline, including Alzheimer’s disease. While the idea of your body benefiting from its own flatulence may sound absurd, the study, published in Proceedings of the National Academies of Science, takes it quite seriously. “Our new data firmly link aging, neurodegeneration and cell signaling using hydrogen sulfide and other gaseous molecules within the cell,” said Dr. Bindu Paul, the study’s lead scientist. What hydrogen sulfide actually does (besides stink) Hydrogen sulfide is toxic in large amounts, but your body naturally produces tiny, controlled doses to regulate everything from blood flow to inflammation. According to Dr. Solomon Snyder, one of the study’s co-authors, the gas plays a role in cell signaling by modifying proteins in a process called sulfhydration. But here’s the kicker: sulfhydration levels decline with age, and even more dramatically in people with Alzheimer’s. “Using the same method, we now confirm a decrease in sulfhydration in the AD brain,” said collaborator Dr. Milos Filipovic, referring to Alzheimer’s disease. In other words, the body’s natural production of hydrogen sulfide may decline just when the brain needs it most. Fart power: tested on mice, with surprising results To explore this link, researchers used genetically modified mice that mimic human Alzheimer’s disease. The mice were injected with NaGYY, a compound that slowly releases hydrogen sulfide into the body. After 12 weeks, the treated mice showed some seriously promising improvements. Behavioral tests revealed that cognitive and motor function improved by 50 percent compared to untreated mice. The ones who received the hydrogen sulfide treatment were more physically active and could better recall the locations of platform edits. This is kind of like remembering where you left your keys. “The results showed that the behavioral outcomes of Alzheimer’s disease could be reversed by introducing hydrogen sulfide,” the research team wrote. The science behind the stink But what exactly was happening in the brain? The study pointed to a common enzyme called GSK3β (glycogen synthase beta), which normally helps regulate cellular processes. When hydrogen sulfide levels are healthy, GSK3β works as a signaling molecule. But in its absence, it starts to stick too closely to another protein called Tau. When Tau and GSK3β bind too often, Tau forms clumps in neurons. Those clumps block communication between nerve cells and eventually cause them to die, a defining feature of Alzheimer’s progression. “This leads to the deterioration and eventual loss of cognition, memory and motor function,” the research team explained. “Understanding the cascade of events is important to designing therapies that can block this interaction like hydrogen sulfide is able to do,” said Daniel Giovinazzo, PhD student and first author of the study. A big whiff of hope Until recently, scientists didn’t have a good way to simulate the body’s precise, low-dose hydrogen sulfide production in lab settings. That changed with the compound NaGYY, which can mimic the body’s natural gas-making abilities. “This compound does just that and shows by correcting brain levels of hydrogen sulfide, we could successfully reverse some aspects of Alzheimer’s disease,” said Dr. Matt Whiteman, one of the study’s co-authors. The team is continuing to explore how adjusting the body’s hydrogen sulfide levels could open new doors for treating neurodegenerative diseases. And while sniffing your own farts probably isn’t the answer, the science behind this sulfurous gas is now being taken seriously by some of the world’s leading medical researchers. Source study: Proceedings of the National Academies of Science—Hydrogen sulfide is neuroprotective in Alzheimer’s disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylationThe post Smelling your own farts might be good for your brain, science says first appeared on The Optimist Daily: Making Solutions the News.
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The Lighter Side
The Lighter Side
4 w

Decades of protection pay off as endangered whales make a rare comeback in Canada
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Decades of protection pay off as endangered whales make a rare comeback in Canada

BY THE OPTIMIST DAILY EDITORIAL TEAM In a world where news about endangered species is often bleak, a sprawling underwater canyon off the coast of Nova Scotia is offering something rare: hope. There, in the dark, nutrient-rich waters of the Gully, a vast submarine canyon roughly the size of the Grand Canyon, Canada’s northern bottlenose whales are making a remarkable recovery. Once hunted to near collapse, these deep-diving whales are now rebounding after decades of protection, a new study published in the Journal of Applied Ecology found. “This study really does provide excellent evidence that knowledge of a species, its needs and its threats can be used to generate conservation success,” said Ari Friedlaender, a marine ecologist at the University of California, Santa Cruz, who was not involved in the research. What makes the Gully special The Gully’s dramatic topography consists of steep walls, deep channels, and strong ocean currents, and creates ideal conditions for marine life to flourish. “At the broadest scale, submarine canyons stir up the oceanography, and that typically translates into more productivity, life and food—good for everything!” said Hal Whitehead, marine biologist at Dalhousie University and co-author of the study. This makes the Gully a perfect year-round home for the Scotian Shelf population of northern bottlenose whales, a group classified as endangered by the Committee on the Status of Endangered Wildlife in Canada. Whitehead first encountered these whales in 1977 and was struck by their unusual friendliness. “These wonderful whales came up to the boat. Unlike most whales, they were friendly,” he recalled. “I thought, wow, that’s very cool.” Unfortunately, that same friendliness made them easy targets during the commercial whaling era. Before Canada banned whaling in 1972, whalers exploited their curious nature. “The whales would come around, and they just slaughtered them all,” Whitehead said. From collapse to cautious optimism By the mid-2000s, decades of whaling and continued threats from fishing gear and ship strikes had pushed the Scotian Shelf population to just 130 individuals. But in 2004, a turning point came when Canada designated the Gully as a Marine Protected Area (MPA) under legislation first passed in 1996. This law gave the government authority to protect ecologically valuable marine zones. “We worked with experts to find places that are high value for conservation and good science,” said Paul Macnab, senior oceans biologist and project lead for the Gully MPA. Though not involved in the study, Macnab noted the Gully was chosen as a place where the effectiveness of marine protection could be properly tested. In the Gully’s core zone, commercial fishing and other harmful activities were banned, protecting both the whales and the prey they rely on. Tracking the impact of protection To understand whether the protections were actually helping, researchers used 35 years of observational data, analyzing both whale sightings and human activity in the area. What they found was promising. Fishing and vessel traffic had declined significantly in the heart of the MPA. Meanwhile, the whale population grew by nearly two-thirds, reaching an estimated 210 individuals by 2023. That’s more than were present when Whitehead first studied them nearly five decades ago. A rare marine conservation win Globally, northern bottlenose whales still face challenges. Low birth rates and ongoing risks like fishing gear entanglement continue to slow recovery in other regions. But in the Gully, years of consistent protections and monitoring have paid off. “The Gully is one of the few places where we’ve been able to track a distinct population long enough to see real trends,” said Whitehead. Still, as encouraging as the rebound is, scientists caution that a single protected canyon is not enough. Many marine species, including whales, migrate across vast ocean areas. “For many other species, it’s only part of their habitat, and we have to protect them in a lot of other ways,” Whitehead said. That means developing networks of protected zones that safeguard marine life not just where they feed, but where they travel. The bigger picture The Gully’s whales show what’s possible when science, policy, and long-term monitoring come together. It also highlights how marine protected areas, if properly enforced, can make a measurable difference for endangered species. At a time when biodiversity loss dominates global headlines, the story from this deep-sea canyon is a reminder that recovery is possible with the right tools and commitment. And that, sometimes, protection pays off, not just for whales, but for the planet. Source study: Journal of Applied Ecology—Reversing decline: The impact of spatial conservation on endangered northern bottlenose whalesThe post Decades of protection pay off as endangered whales make a rare comeback in Canada first appeared on The Optimist Daily: Making Solutions the News.
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Living In Faith
Living In Faith
4 w

3 Ways to Let Go of Your Spouse’s Past Mistakes - Crosswalk Couples Devotional - December 10
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3 Ways to Let Go of Your Spouse’s Past Mistakes - Crosswalk Couples Devotional - December 10

Unlike football, it’s not good to keep score in marriage.
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Daily Caller Feed
Daily Caller Feed
4 w

Was Shedeur Sanders Wearing Thong During Browns-Titans Game?
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Was Shedeur Sanders Wearing Thong During Browns-Titans Game?

This is pure comedy
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Twitchy Feed
Twitchy Feed
4 w

Political Prey: Elon Musk Says Charlie Kirk’s Murder Means He Can’t Risk Going Out in General Public
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twitchy.com

Political Prey: Elon Musk Says Charlie Kirk’s Murder Means He Can’t Risk Going Out in General Public

Political Prey: Elon Musk Says Charlie Kirk’s Murder Means He Can’t Risk Going Out in General Public
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YubNub News
YubNub News
4 w

BIG: DOJ Kills the ‘Nuclear Weapon’ of ‘Systemic Racism’
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BIG: DOJ Kills the ‘Nuclear Weapon’ of ‘Systemic Racism’

This is big. The premise of systemic racism and its ‘solution’ equity is that you can establish that America is just as racist as ever, all evidence to the contrary, is disparate impact. What that…
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YubNub News
YubNub News
4 w

Former SNL Star David Spade Slams Mall Christmas Tree-Lighting Event for Refusing to Say the Word ‘Christmas’ (VIDEO)
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Former SNL Star David Spade Slams Mall Christmas Tree-Lighting Event for Refusing to Say the Word ‘Christmas’ (VIDEO)

SNL alums David Spade and Dana Carvey – Screencap of YouTube video. Political correctness around Christmas has gotten so out of hand that even people who work in the entertainment industry have noticed…
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YubNub News
YubNub News
4 w

Elissa Slotkin Suddenly Claims Democrats Made the ‘Illegal Orders’ Video Because They Were Approached by Concerned Military Members (VIDEO)
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Elissa Slotkin Suddenly Claims Democrats Made the ‘Illegal Orders’ Video Because They Were Approached by Concerned Military Members (VIDEO)

Elissa Slotkin – Screencap of Twitter/X video. Weeks after Elissa Slotkin and other Democrats released a bizarre and seditious video, telling members of the U.S. Military that it was OK to refuse supposedly…
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YubNub News
YubNub News
4 w

Kamala: “There Will Be a Marble Bust of Me in Congress”
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Kamala: “There Will Be a Marble Bust of Me in Congress”

Kamala Harris is still around. Most Democrats wish she weren’t. And she insists on reminding everyone of why. It’s gotten so bad that there should be a TV show, “Kamala says the darndest things.”…
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YubNub News
YubNub News
4 w

MEMO: Joe Biden Was Warned His Immigration Policies Would Cause Chaos at the Southern Border – He Did it Anyway
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MEMO: Joe Biden Was Warned His Immigration Policies Would Cause Chaos at the Southern Border – He Did it Anyway

Screencap of YouTube video. As much as it seems like Joe Biden was not mentally present throughout his presidency and did not really have any idea what was going on, he apparently did get some warnings…
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