Rocket Pharmaceuticals said on Friday the U.S. health regulator declined to approve its gene therapy to treat a rare and severe pediatric disorder that causes the immune system to malfunction, sending its shares down more than 12% in early trading. The Food and Drug...

A measure of prices that is closely tracked by the Federal Reserve suggests that inflation pressures in the U.S. economy are continuing to ease.

Former Obama administration official David Axelrod warned GOP strategists if President Joe Biden is replaced at the top of the Democratic ticket, they'd be "in trouble with Donald Trump."

The Supreme Court decided on Friday that cities can enforce bans on homeless people sleeping outdoors in West Coast areas where shelter space is lacking.

Prosecutors expect to call their final witness on Friday in U.S. Sen. Bob Menendez's corruption trial, paving the way for the once-powerful lawmaker to mount his defense.

The amphibious assault ship USS Wasp entered the eastern Mediterranean Sea this week as the U.S. positions warships to try to keep fighting between Israel and Hezbollah in Lebanon from escalating into a wider war in the Middle East.

The Iowa Supreme Court said Friday the state's strict abortion law is legal, telling a lower court to dissolve a temporary block on the law and allowing Iowa to ban most abortions after about six weeks of pregnancy - before many women know they are pregnant.

The Supreme Court on Friday upended a 40-year-old decision that made it easier for the federal government to regulate the environment, public health, workplace safety and consumer protections, delivering a far-reaching and potentially lucrative victory to business...

The Biden administration will expand deportation relief and work permits to an estimated 309,000 Haitians in the country already, the U.S. Department of Homeland Security said on Friday.

Hearty, easy and delicious, The Best Crock Pot Meatloaf is a true comfort meal that you cook low and slow with the perfect sweet and tangy glaze. A truly delicious family meal! HOMEMADE MEATLOAF IN THE SLOW COOKER If you are looking for a super comforting and easy dinner time meal, then you need to make this Crock Pot Meatloaf. Meatloaf has always been one of my go-to comfort foods all year round. This Crock Pot Meatloaf is one of my favorite recipes, you set it and forget it and in the end you have a tasty meal that you can serve it with creamy mashed potatoes and some mixed vegetables. No need to even turn on the oven! FREQUENTLY ASKED QUESTIONS: Do I need to use panko breadcrumbs? Nope. You can use regular breadcrumbs or even small torn up pieces of bread (about 3 pieces.) What type of ground beef should I use? For this recipe, I recommend a leaner ground beef so it produces less grease (about an 85/15 or higher) Can I use ground turkey? Yes as well as ground chicken. For an Italian twist, try mixing a combination of ground beef and Italian sausage. Can this meatloaf be made in the oven? Absolutely! You can make it in the oven, in the Instant Pot or in an Air Fryer. Click on only of those links to see how to do it! How do I store leftovers? This Crock Pot Meatloaf Recipe requires storage in the refrigerator. Place in an airtight container and it should last up to 3-4 days. To reheat, just place your portion on a microwave safe plate and microwave until heated through.Place the Crock Pot Meatloaf in the freezer and it should last up to 6 months. To reheat: the fastest way is to microwave on a microwave-safe plate in increments until heated through. INGREDIENTS NEEDED: (FULL RECIPE AT THE BOTTOM OF THE POST) sweet onion – I like the finely grate the oven so there isn’t larger chunks in there but that is totally up to you. milk eggs – I think it’s a good idea to beat the eggs before adding them to the mixture so they combine easier but you do what is easiest for you to prepare this meatloaf. light brown sugar – if you don’t like a sweet glaze, just leave it out. ketchup bbq sauce – use your favorite or even use a Homemade BBQ Sauce or if you don’t like BBQ sauce, just leave it out. Worcestershire sauce garlic powder panko breadcrumbs – regular breadcrumbs can be used as well. ground beef – ground turkey or ground chicken can be used. Go with a slightly leaner beef if you can so it produces less grease. HOW TO MAKE CROCK POT MEATLOAF: Line the crock pot with a large piece of heavy-duty foil, spray with cooking spray, and set aside. In a large bowl add the grated onion, milk, eggs, brown sugar, ketchup, bbq sauce, Worcestershire sauce, garlic powder, salt, and pepper. Whisk this mixture until fully combined. Add in the breadcrumbs.Stir in the breadcrumbs until mixed through. Add the ground beef. Using your clean hands, mix everything together until well combined but do not over mix. Add the mixture to the slow cooker, and form it into a long oval shape, set aside. In a small bowl add the ketchup, bbq sauce, and brown sugar. Whisk this mixture together to make the glaze. Brush half of the glaze on top of the meatloaf. Cook on low for 6 hours or until the internal temperature reaches at least 165°F. Take the meatloaf out of the crockpot using the foil to help lift it out. Place on a sheet tray and brush the remaining glaze on top. Optional: Broil in the oven until the glaze is bubbly and starts to brown slightly. Serve topped with chopped parsley (optional). Then slice and enjoy! CRAVING MORE RECIPES? Crock Pot Salisbury Steak Air Fryer Meatloaf Crock Pot Lasagna Crock Pot Pork Loin Meatloaf Patty Melts Instant Pot Meatloaf Momma’s Best Meatloaf Crock Pot Meatloaf Meatballs Mozzarella Stuffed BBQ Meatloaf Butter Swim Biscuits Stovetop Mashed Potatoes Originally published: January 2021Updated and republished: June 2024 Print Crock Pot Meatloaf Hearty, easy and delicious, The Best Crock Pot Meatloaf is a true comfort meal that you cook low and slow with the perfect sweet and tangy glaze. No oven needed! Course Main CourseCuisine American Prep Time 15 minutes minutesCook Time 6 hours hoursTotal Time 6 hours hours 15 minutes minutes Servings 8 Calories 461kcal Author Brandie @ The Country Cook IngredientsFor the meatloaf:1 small sweet onion, peeled and grated1 cup whole milk2 large eggs, lightly beaten2 Tablespoons light brown sugar, packed1 Tablespoon ketchup1 Tablespoon bbq sauce1 Tablespoon Worcestershire sauce1 Tablespoon garlic powder1 teaspoon kosher salt½ teaspoon black pepper1 cup plain panko breadcrumbs2 pounds (85/15) ground beefFor the glaze:½ cup ketchup½ cup bbq sauce¼ cup light brown sugar, packedfresh chopped parsley, for garnish (optional) InstructionsLine the crock pot with a large piece of heavy-duty foil, spray with cooking spray, and set aside. In a large bowl add 1 small sweet onion, peeled and grated, 1 cup whole milk, 2 large eggs, lightly beaten, 2 Tablespoons light brown sugar, packed, 1 Tablespoon ketchup, 1 Tablespoon bbq sauce, 1 Tablespoon Worcestershire sauce, 1 Tablespoon garlic powder, 1 teaspoon kosher salt and ½ teaspoon black pepper. Whisk this mixture until fully combined. Add in 1 cup plain panko breadcrumbs. Stir in the breadcrumbs until mixed well. Next, add 2 pounds (85/15) ground beef. Using your clean hands, mix everything together until well combined but do not over mix. Add the mixture to the aluminum foil in the slow cooker, and form it into a long oval shape, set aside. In a small bowl add ½ cup ketchup, ½ cup bbq sauce and ¼ cup light brown sugar, packed. Whisk this mixture together to make the glaze. Brush half of the glaze on top of the meatloaf. Cook on low for 6 hours or until the internal temperature reaches at least 165°F. Take the meatloaf out of the crockpot using the foil to help lift it out. Place on a sheet tray and brush the remaining glaze on top. Optional: Broil in the oven until the glaze is bubbly and starts to brown slightly. Serve topped with fresh chopped parsley, for garnish. Video Notes Using a leaner meat such as an 85/15 like we did or this recipe helps with excess grease. Do not over mix you meat mixture, this will make the meatloaf tough. This Crock Pot Meatloaf can also be made in the oven, mix as directed then shape into a patty on a lined baking pan and bake at 350 for 60 minutes until internal temperature reaches 160 degrees F. NutritionCalories: 461kcal | Carbohydrates: 34g | Protein: 24g | Fat: 25g | Sodium: 837mg | Fiber: 1g | Sugar: 24g