https://www.medrxiv.org/conten....t/10.1101/2021.08.24
CDC STUDY SHOWS THREE-FOURTHS OF PEOPLE INFECTED IN MASSACHUSETTS CORONAVIRUS OUTBREAK WERE VACCINATED BUT FEW REQUIRED HOSPITALIZATION
https://www.washingtonpost.com..../health/2021/07/30/p
GEERT VANDEN BOSSCHE, PHD, DVM HTTPS://TWITTER.COM/GVDBOSSCHE HTTPS://WWW.GEERTVANDENBOSSCHE.ORG/
Credentials-
GSK Biologicals:
Senior Project Leader 'Adolescent Vaccine Projects'
New BioTech Vaccine Development and QC-QA Manager
Head of Adjuvant Technologies and Alternative Deliveries, R&D
Novartis Vaccines & Diagnostics: Director Research Program Leader and Head of Adjuvants
Solvay Biologicals: Global Project Director Influenza Vaccines
Bill & Melinda Gates Foundation (MMGF): Senior Program Officer, Global Health, Vaccine Discovery
Global Alliance for Vaccines and Immunisation (GAVI): Program Manager
UNIVAC: Chief Innovation & Scientific Officer
German Centre for Infection Research (DZIF): Head of the Vaccine Development Office
VARECO: Managing Director
*He is NOT an anti-vaxer (obviously), and yet he does NOT recommend getting the covid vaccines. The specific antibodies introduced via the covid vaccines out-compete our intrinsic antibodies for an extended period of time... perhaps irrevocably.
WHY DO WE ALWAYS NEED TO LEARN THINGS THE HARD WAY?
Summary, key lessons and conclusions
COMPARING SARS-COV-2 NATURAL IMMUNITY TO VACCINE-INDUCED IMMUNITY: REINFECTIONS VERSUS BREAKTHROUGH INFECTIONS
RESULTS:
SARS-CoV-2-naïve vaccinees had a 13.06-fold increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant (P<0.001) for symptomatic disease as well. When allowing the infection to occur at any time before vaccination (from March 2020 to February 2021), evidence of waning natural immunity was demonstrated, though SARS-CoV-2 naïve vaccinees had a 5.96-fold increased risk for breakthrough infection and a 7.13-fold increased risk for symptomatic disease. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalizations compared to those that were previously infected.
CONCLUSIONS:
This study demonstrated that natural immunity confers longer lasting and stronger protection against infection, symptomatic disease and hospitalization caused by the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity. Individuals who were both previously infected with SARS-CoV-2 and given a single dose of the vaccine gained additional protection against the Delta variant.
RESULTS:
Model 1 – previously infected vs. vaccinated individuals, with matching for time of first event
After adjusting for comorbidities, we found a statistically significant 13.06-fold increased risk for breakthrough infection as opposed to reinfection.
As for symptomatic SARS-COV-2 infections during the follow-up period, 199 cases were recorded, 191 of which were in the vaccinated group and 8 in the previously infected group.
After adjusting for comorbidities, we found a 27.02-fold risk for symptomatic breakthrough infection as opposed to symptomatic reinfection.
Nine cases of COVID-19-related hospitalizations were recorded, 8 of which were in the vaccinated group and 1 in the previously infected group.
Model 2 –previously infected vs. vaccinated individuals, without matching for time of first event
When comparing the vaccinated individuals to those previously infected at any time (including during 202, we found that throughout the follow-up period, 748 cases of SARS-CoV-2 infection were recorded, 640 of which were in the vaccinated group (breakthrough infections) and 108 in the previously infected group (reinfections).
After adjusting for comorbidities, a 5.96-fold increased risk for breakthrough infection as opposed to reinfection could be observed.
Overall, 552 symptomatic cases of SARS-CoV-2 were recorded, 484 in the vaccinated group and 68 in the previously infected group. There was a 7.13-fold increased risk for symptomatic breakthrough infection than symptomatic reinfection. COVID-19 related hospitalizations occurred in 4 and 21 of the reinfection and breakthrough infection groups, respectively. Vaccinated individuals had a 6.7-fold increased to be admitted compared to recovered individuals. Being 60 years of age or older significantly increased the risk of COVID-19-related hospitalizations.
DISCUSSION:
This is the largest real-world observational study comparing natural immunity, gained through previous SARS-CoV-2 infection, to vaccine-induced immunity, afforded by the BNT162b2 mRNA vaccine. Our large cohort, enabled by Israel’s rapid rollout of the mass-vaccination campaign, allowed us to investigate the risk for additional infection – either a breakthrough infection in vaccinated individuals or reinfection in previously infected ones – over a longer period than thus far described. Our analysis demonstrates that SARS-CoV-2-naïve vaccinees had a 13.06-fold increased risk for breakthrough infection with the Delta variant compared to those previously infected, when the first event (infection or vaccination) occurred during January and February of 2021. The increased risk was significant for a symptomatic disease as well.
Broadening the research question to examine the extent of the phenomenon, we allowed the infection to occur at any time between March 2020 to February 2021 (when different variants were dominant in Israel), compared to vaccination only in January and February 2021. Although the results could suggest waning natural immunity against the Delta variant, those vaccinated are still at a 5.96-fold increased risk for breakthrough infection and at a 7.13-fold increased risk for symptomatic disease compared to those previously infected. SARS-CoV-2-naïve vaccinees were also at a greater risk for COVID-19-related-hospitalization compared to those who were previously infected.
This analysis demonstrated that natural immunity affords longer lasting and stronger protection against infection, symptomatic disease and hospitalization due to the Delta variant of SARS-CoV-2, compared to the BNT162b2 two-dose vaccine-induced immunity.
Swiss Policy Research - Facts about Covid-19
*As of September 2021, all emphasis added
1. Lethality: According to the latest immunological studies, the overall infection fatality rate (IFR) of covid-19 in the general population is about 0.1% to 0.5% in most countries, which is most closely comparable to the medium influenza pandemics of 1936, 1957 and 1968.
2. Treatment: For people at high risk or high exposure, early or prophylactic treatment is essential to prevent progression of the disease. According to numerous international studies, early outpatient treatment of covid may significantly reduce hospitalizations and deaths.
https://swprs.org/on-the-treatment-of-covid-19/
3. Age profile: The median age of covid deaths is over 80 years in most Western countries (78 in the US) and about 5% of the deceased had no serious preconditions. The age and risk profile of covid mortality is therefore comparable to normal mortality, but increases it proportionally.
4. Nursing homes: In many Western countries, about 50% of all covid deaths have occurred in nursing homes, which require targeted and humane protection. In some cases, care home residents died NOT from the coronavirus, but from weeks of stress and isolation.
5. Excess mortality: To date, the pandemic increased mortality by 5% to 25% in most Western countries. Up to 25% of the additional deaths were caused NOT by covid, but by indirect effects of the pandemic and lockdowns (e.g. fewer treatments of cancer and heart attack patients).
6. Antibodies: By the end of 2020, antibody seroprevalence was between 10% and 30% of the population in most Western countries. At seroprevalence levels above 30%, a significant decrease in the infection rate was observed in many regions.
7. Symptoms: About 30% of all infected persons show no symptoms. Overall, about 95% of all people develop at most mild or moderate symptoms and do not require hospitalization. Early outpatient treatment may significantly reduce hospitalizations.
10. Masks: There is still LITTLE TO NO scientific evidence for the effectiveness of face masks in the general population, and the introduction of mandatory masks couldn’t contain or slow the epidemic in most countries. If used improperly, masks may increase the risk of infection.
11. Children and schools: In contrast to influenza, the risk of disease and transmission in children is rather low in the case of covid. There was and is therefore NO MEDICAL REASON for the closure of elementary schools or other measures specifically aimed at children.
12. Vaccines: Real-world studies have shown a very high, but rapidly declining effectiveness of covid vaccines. Numerous severe and fatal vaccine adverse events have been reported even in young people. A previous covid infection provides much better protection than vaccination.
https://swprs.org/covid-vaccine-adverse-events/
https://www.openvaers.com/covid-data/mortality - 13,911 as of 8/27/21
13. Contact tracing: A WHO study of 2019 on measures against influenza pandemics concluded that from a medical perspective, contact tracing is “NOT recommended in any circumstances”. Contact tracing apps on cell phones have also proven ineffective in most countries.
14. PCR tests: The highly sensitive PCR test kits may in some cases produce FALSE POSITIVE or FALSE NEGATIVE results or react to non-infectious virus fragments from a previous infection. In this regard, the so-called cycle threshold or ct value is an important parameter.
16. Lockdowns: In contrast to early border controls, lockdowns have had NO SIGNIFICANT effect on the pandemic. According to the UN, lockdowns may put the livelihood of 1.6 billion people at acute risk and may push an additional 150 million children into poverty.
18. Media: The reporting of many media has been UNPROFESSIONAL, has INCREASED FEAR AND PANIC in the population and has led to a HUNDREDFOLD OVERESTIMATION of the lethality of the coronavirus. Some media even used manipulative pictures and videos to dramatize the situation.
-Coronavirus disease 2019: The harms of exaggerated information and non-evidence-based measures, European Journal of Clinical Investigation
https://onlinelibrary.wiley.co....m/doi/full/10.1111/e
https://swprs.org/facts-about-....covid-19/?fbclid=IwA