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2 yrs

Novel insights into antibody aggregation expected to open up new avenues for research and therapeutic applications

Novel insights into antibody aggregation expected to open up new avenues for research and therapeutic applications

Antibodies (immunoglobulins) are Y-shaped proteins that recognize and neutralize specific pathogens. Their ability to target specific molecules or cells has made them promising candidates for future drug development. However‚ their light chains—parts of the antibody that contribute to recognizing and binding to specific antigens—misfold and aggregate‚ leading to amyloidosis‚ a condition that brings about complications and tissue dysfunction in the body.

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2 yrs

Researchers safely integrate fragile 2D materials into devices‚ opening a path to unique electronic properties

Researchers safely integrate fragile 2D materials into devices‚ opening a path to unique electronic properties

Two-dimensional materials‚ which are only a few atoms thick‚ can exhibit some incredible properties‚ such as the ability to carry electric charge extremely efficiently‚ which could boost the performance of next-generation electronic devices.

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2 yrs

Researchers quantify the onset of turbulence in a pipe bent back on itself

Researchers quantify the onset of turbulence in a pipe bent back on itself

How much stress do pipes undergo when a liquid flows through them‚ and how does it depend on the degree of curvature of the pipe?

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2 yrs

Spinning up control: Propeller shape helps direct nanoparticles‚ researchers say

Spinning up control: Propeller shape helps direct nanoparticles‚ researchers say

Self-propelled nanoparticles could potentially advance drug delivery and lab-on-a-chip systems—but they are prone to go rogue with random‚ directionless movements. Now‚ an international team of researchers has developed an approach to rein in the synthetic particles.

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2 yrs

Researchers discover a mechanism that controls the identity of stem cells

Researchers discover a mechanism that controls the identity of stem cells

Researchers at the University of California‚ Irvine‚ discovered a mechanism that controls the identity of stem cells. When this mechanism fails‚ embryonic stem cells revert back in time and become totipotent.

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2 yrs

How 'listening' to archaeological sites could shed light on the past

How 'listening' to archaeological sites could shed light on the past

Until recently‚ archaeologists have mostly relied on what they can see at the sites of ancient ruins to unlock the secrets of the past. But lately‚ new methods have started to allow researchers to use other senses to explore these sites in different ways.

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2 yrs

Nanoparticle flu vaccine design shows promise in early tests

Nanoparticle flu vaccine design shows promise in early tests

Existing flu vaccines provide only limited‚ seasonal protection because they target highly changeable proteins on the virus. Scripps Research scientists have now designed a vaccine that should work broadly against influenza A strains—one of the two types of flu virus that normally circulate in humans.

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2 yrs

Orangutan male success not due to dominance alone‚ study finds

Orangutan male success not due to dominance alone‚ study finds

In primates‚ the biggest‚ bossiest males usually get to father the most offspring; and for a long time it was thought that this rule applied to orangutans too. Male orangutans openly compete; and it's the older males with hefty cheek pads‚ known as "flanges‚" who usually get their way when they want to mate. But for wild orangutans‚ nobody knew for sure which males actually won the ultimate prize of fathering offspring.

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2 yrs

Six-million-year-old groundwater pool discovered deep under Sicilian mountains

Six-million-year-old groundwater pool discovered deep under Sicilian mountains

A multi-institutional team of geoscientists has discovered a deep‚ ancient underground pool of fresh water underneath part of the Sicilian mountains. In their study‚ reported in the journal Communications Earth &; Environment‚ the group used publicly available data gathered from oil discovery efforts to study the groundwater in and around the Gela formation beneath the mountains on the island of Sicily.

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2 yrs

Study suggests climate played a crucial role in human migration from Africa

Study suggests climate played a crucial role in human migration from Africa

About 6 million years ago‚ in the deep forests of eastern Africa‚ something spectacular happened. Chimpanzees‚ our closest relative in the animal kingdom‚ evolved in one direction‚ while our earliest ancestors continued in another.

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