from Infowars:  TRUTH LIVES on at https://sgtreport.tv/

from Revolver News: Tension and civil unrest mounting in Ireland in aftermath of immigrant Algerian knife attack against multiple children… People have had enough… Crowds erupting in anger… Chaos… TRUTH LIVES on at https://sgtreport.tv/ Massive numbers of Irish on the streets tonight after an Algerian immigrant stabbed kids outside a school. #IrelandisFull pic.twitter.com/Vzlbjdn5Il — MichaeloKeeffe (@Mick_O_Keeffe) […]

by Jake Welch‚ The National Pulse: Former President Donald Trump will visit Argentina’s newly-elected libertarian populist President Javier Milei in Buenos Aires following a conversation between the two‚ the latter’s press team has announced. The dates of the visit are‚ however‚ yet to be made public. The 45th President publicly congratulated Milei for his success in the Argentinian elections earlier this […]

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A Prayer for When Giving Thanks Is HardBy Molly Law  "Rejoice always‚ pray continually‚ give thanks in all circumstances; for this is God's will for you in Christ Jesus." –1 Thessalonians 5:16-18 The holidays are never cut and dry. Even though it feels as though life should be put on hold for the most joyous time of the year‚ unfortunately‚ it just doesn't work that way. I cannot describe what Christmas time does to me. It fills me with such unbridled joy - joy that I remember feeling as a child‚ joy in the way it brings families together. I await this feeling all year long. As I tend to feel more depressed during the Summer (I know few who feel this way during the summer rather than the winter)‚ when the weather starts to turn‚ the leaves begin to color and then fall‚ and I feel the descent of the holidays‚ it erases that season and I feel joy in life once more. Of course‚ as I said‚ it's not that simple. Tragedy doesn't wait for the holidays to be over - it doesn't hold off until the day after Christmas to strike.  Tragedy‚ any sort of tragedy‚ is terrible no matter what time of year it is‚ yet it doesn't contrast with "the most wonderful time of the year" like it does around the holidays. When something tragic happens with the backdrop of Thanksgiving and Christmas‚ it adds another level of grief that would not be there at any other time.  It can evoke shame when the whole world is telling you "‘tis the season to be jolly!" It can cause us to hide and suppress our feelings when we are gathered around the Thanksgiving table with our families - not wanting to be the one to place a dark cloud over the festivities.  Life cannot and will not stop for anything. Whereas Thanksgiving and Christmas are wonderful times to give thanks and celebrate the birth of our Savior‚ they shouldn't be times where we ignore someone else's pain all in the name of Christmas cheer. It can be tempting to ignore‚ especially if our loved one does not volunteer what they are going through and just enjoy the holiday season.  This time of year is not just about the gifts‚ the songs‚ the food‚ and the decorations. It's a season of remembrance‚ it's a season of giving and serving those around us just as the King of Kings left his home in heaven to come to earth in the most vulnerable form - a baby - to grow‚ live‚ and die a brutal death on a cross for us. Let's Pray: Dear Lord‚This year‚ the holidays will not be joy-filled as many have gone through unimaginable tragedy. I pray that as their family‚ friends‚ and coworkers that we show love‚ compassion‚ and understanding. I pray that we do not ignore anyone's pain all in the name of having the perfect Christmas. I pray that our homes will be welcoming - that everyone knows that no matter what has happened‚ it is a safe place to be. I pray that no one will feel like they have to skip the holidays because they do not want to "bring everybody else down with them." Please‚ God‚ be with everyone who has experienced tragedy this year and close to the holidays. I pray that this season it doesn't have to be either‚ or - for life is an amalgamation of darkness and light. I pray that right alongside of pain that joy can be felt in the same beat. I hope everyone knows that it is okay to feel both at the same time. Please bring us comfort and peace in our time of mourning. Give us people who are caring and understanding. I pray that we turn to you to feel your overwhelming presence‚ where you cry with us‚ you comfort us‚ and take our burdens as your own. Thank you for revealing your love for us by sacrificing your Son for his entire life on earth and in death. As a Father‚ I can't imagine how acutely you felt that pain yourself. I know full well that you know our pain and can shoulder anything we go through. I pray that we‚ as Christians‚ follow your example and live in your image for those around us. We love and trust you with all of our hearts‚ our Father and Savior.In Jesus' precious name‚ Amen.  Photo credit: ©Getty Images/Christin Lola Molly Law is the Editor of C.com. She has a Master of Arts in Publishing Studies from the University of Stirling‚ UK‚ where she studied and lived for a year in Scotland. She has a Bachelor of Arts in English Professional Writing from Gardner-Webb University. Her editorial career includes Senior Editor of a bimonthly magazine for the nonprofit ACA and Editorial Assistant at Luath Press in Edinburgh‚ UK. She enjoys reading 18th-century British Literature‚ creative writing‚ and traveling.  LISTEN to More Christmas Prayers on LifeAudio Teach Us to Pray is a FREE prayer podcast hosted by iBelieve writer Christina Patterson. Each week‚ she gives you practical‚ real-life tips on how to grow your faith and relationship with God through the power of prayer. To listen to her episode on What to Pray in the Morning for a Worry-Free Day‚ click below! Now that you’ve prayed‚ are you in need of someone to pray for YOU? Click the button below! Visit iBelieve.com for more inspiring prayer content. The post A Prayer When Giving Thanks Is Hard – Your Daily Prayer – November 25 appeared first on GodUpdates.

According to a new study‚ a molecule found in beef and dairy improves the immune response to cancer. “Scientists at UChicago discover that trans-vaccenic acid (TVA)‚ a fatty acid found in beef‚ lamb‚ and dairy products‚ improves the ability of immune cells to fight tumors‚” The University of Chicago Biological Sciences Division wrote Wednesday. The researchers determined that “cancer patients with higher levels of the compound in their blood responded better to treatment‚ suggesting that it could have major benefits as a nutritional supplement‚” Daily Mail reports. Blow to veganism? Nutrient found in beef and dairy helps fight cancerhttps://t.co/XedkQLBDi5 — Wittgenstein (@backtolife_2023) November 24‚ 2023 WATCH: Scientists have found eating beef and dairy products could help our immune system kill some cancers. The fatty acid produced by grazing animals improves the ability of certain cells to infiltrate tumours. https://t.co/TWh1KQh9q4 #7NEWS pic.twitter.com/L12HjAKlgv — 7NEWS Sydney (@7NewsSydney) November 24‚ 2023 “The research‚ published this week in Nature‚ also shows that patients with higher levels of TVA circulating in the blood responded better to immunotherapy‚ suggesting that it could have potential as a nutritional supplement to complement clinical treatments for cancer‚” The University of Chicago Biological Sciences Division stated. “There are many studies trying to decipher the link between diet and human health‚ and it’s very difficult to understand the underlying mechanisms because of the wide variety of foods people eat. But if we focus on just the nutrients and metabolites derived from food‚ we begin to see how they influence physiology and pathology‚” said Jing Chen‚ PhD‚ the Janet Davison Rowley Distinguished Service Professor of Medicine at UChicago and one of the senior authors of the new study. “By focusing on nutrients that can activate T cell responses‚ we found one that actually enhances anti-tumor immunity by activating an important immune pathway‚” Chen added. From The University of Chicago Biological Sciences Division: Chen’s lab focuses on understanding how metabolites‚ nutrients and other molecules circulating in the blood influence the development of cancer and response to cancer treatments. For the new study‚ two postdoctoral fellows‚ Hao Fan‚ PhD and Siyuan Xia‚ PhD‚ both co-first authors‚ assembled a “blood nutrient” compound library consisting of 255 bioactive molecules derived from nutrients. They screened the compounds in this new library for their ability to influence anti-tumor immunity by activating CD8+ T cells‚ a group of immune cells critical for killing cancerous or virally infected cells. After the scientists evaluated the top six candidates in both human and mouse cells‚ they saw that TVA performed the best. TVA is the most abundant trans fatty acid present in human milk‚ but the body cannot produce it on its own. Only about 20% of TVA is broken down into other byproducts‚ leaving 80% circulating in the blood. “That means there must be something else it does‚ so we started working on it more‚” Chen said. The researchers then conducted a series of experiments with cells and mouse models of diverse tumor types. Feeding mice a diet enriched with TVA significantly reduced the tumor growth potential of melanoma and colon cancer cells compared to mice fed a control diet. The TVA diet also enhanced the ability of CD8+ T cells to infiltrate tumors. The team also performed a series of molecular and genetic analyses to understand how TVA was affecting the T cells. These included a new technique for monitoring transcription of single-stranded DNA called kethoxal-assisted single-stranded DNA sequencing‚ or KAS-seq‚ developed by Chuan He‚ PhD‚ the John T. Wilson Distinguished Service Professor of Chemistry at UChicago and another senior author of the study. These additional assays‚ done by both the Chen and He labs‚ showed that TVA inactivates a receptor on the cell surface called GPR43 which is usually activated by short-chain fatty acids often produced by gut microbiota. TVA overpowers these short-chain fatty acids and activates a cellular signaling process known as the CREB pathway‚ which is involved in a variety of functions including cellular growth‚ survival‚ and differentiation. The team also showed that mouse models where the GPR43 receptor was exclusively removed from CD8+ T cells also lacked their improved tumor fighting ability. Eating beef staves off cancer!! pic.twitter.com/QeeliWuiWX — Dr Shawn Baker (@SBakerMD) November 22‚ 2023 Daily Mail reports: Fatty cuts of beef and lamb are more likely to have higher levels of TVA compared to lean cuts‚ as are whole milk and full-fat dairy products compared to low-fat and skim. The anti-cancer power of the dairy-derived fatty acid comes from its ability to turbocharge certain immune cells known as T cells‚ which recognize foreign invaders and prompt the immune system to kill them. Researchers said that eating foods rich in this compound or giving it to cancer patients as a supplement could have measurable benefits in decreasing the size of tumors. Dr Jing Chen‚ senior author of the study‚ said: ‘By focusing on nutrients that can activate T cell responses‚ we found one that actually enhances anti-tumor immunity by activating an important immune pathway.’ Her team identified the nutrient after combing through a database of around 700 different metabolites – substances produced when the body breaks down food – all of which came from food. Read the abstract for the study‚ titled “Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity‚” at Nature: Diet-derived nutrients are inextricably linked to human physiology by providing energy and biosynthetic building blocks and by functioning as regulatory molecules. However‚ the mechanisms by which circulating nutrients in the human body influence specific physiological processes remain largely unknown. Here we use a blood nutrient compound library-based screening approach to demonstrate that dietary trans-vaccenic acid (TVA) directly promotes effector CD8+ T cell function and anti-tumour immunity in vivo. TVA is the predominant form of trans-fatty acids enriched in human milk‚ but the human body cannot produce TVA endogenously1. Circulating TVA in humans is mainly from ruminant-derived foods including beef‚ lamb and dairy products such as milk and butter2‚3‚ but only around 19% or 12% of dietary TVA is converted to rumenic acid by humans or mice‚ respectively4‚5. Mechanistically‚ TVA inactivates the cell-surface receptor GPR43‚ an immunomodulatory G protein-coupled receptor activated by its short-chain fatty acid ligands6‚7‚8. TVA thus antagonizes the short-chain fatty acid agonists of GPR43‚ leading to activation of the cAMP–PKA–CREB axis for enhanced CD8+ T cell function. These findings reveal that diet-derived TVA represents a mechanism for host-extrinsic reprogramming of CD8+ T cells as opposed to the intrahost gut microbiota-derived short-chain fatty acids. TVA thus has translational potential for the treatment of tumours.