A multi-institutional team led by University of Washington scientists have engineered a new vaccine platform combining mRNA and computational protein design, producing in mice a potent immune defense against both Wuhan-Hu-1 and omicron BA.5 SARS-CoV-2.

The drug development pipeline is a costly and lengthy process. Identifying high-quality "hit" compounds—those with high potency, selectivity, and favorable metabolic properties—at the earliest stages is important for reducing cost and accelerating the path to clinical trials. For the last decade, scientists have looked to machine learning to make this initial screening process more efficient.

Leishmaniasis belongs to the class of neglected tropical diseases (NTDs) that particularly affect people in the poorest tropical regions of the world. NTDs are less studied and therapeutically addressed than other diseases.

New research led by Flinders University has shed light on one of chemistry's big mysteries by describing how simple salts exist near the surface of liquid solvents.

A glass plate, a delicate tube and an oil bath are all that is required: thanks to a new method, researchers at ETH Zurich can produce tens of thousands of tiny droplets within minutes. This enables them to test enzymes and active ingredients faster, more precisely and in a more resource-efficient manner than previously.

Researchers from the Institute of Polymer Science and Engineering at National Taiwan University have developed a multifunctional hydrogel sensor for detecting formaldehyde.

Professor Kenzo Kaifu and Research Fellow Hiromi Shiraishi of Chuo University, together with Professor Yu-Shan Han of National Taiwan University, conducted the world's first quantitative study to reveal the global consumption structure of freshwater eels (genus Anguilla).

Shock waves should not be shocking—engineers across scientific fields need to be able to precisely predict how the instant and strong pressure changes initiate and dissipate to prevent damage. Now, thanks to a team from Yokohama National University, those predictions are even better understood.

The Orionids—one of two major meteor showers caused by remnants from Halley's comet—will peak with the arrival of a new moon, providing an excellent opportunity to see shooting stars without interference from moonlight.

When the volcanic island of Surtsey rose from the North Atlantic Ocean in 1963, it offered scientists a once-in-a-lifetime opportunity to observe how life takes hold on brand-new and barren land. For decades, ecologists believed that plants' ability to reach remote and isolated places depended mainly on special adaptations for long-distance dispersal—for example, fleshy fruits thought to attract birds, which would eat the fruit and later disperse the seeds—giving those species a decisive advantage in colonizing new areas.