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Can Gut Bacteria Help Detox the Body from Forever Chemicals?
The Shocking Power of Bacteria To Remove Poisons
Modern life is full of conveniences—from nonstick pans and waterproof jackets to fast food wrappers and makeup. But many of these products contain a group of synthetic chemicals known as PFAS, short for per- and polyfluoroalkyl substances.
These “forever chemicals” earned their nickname because they barely break down in the environment or in the human body. Over time, they build up in our tissues, where they’ve been linked to serious health problems including cancer, liver damage, and immune disorders.
PFAS are everywhere—in our water, soil, food, and even in our blood. Despite growing awareness of their dangers, no approved method currently exists to reliably remove them from the human body.
But new research offers a surprising ally in the fight against these toxic invaders: the bacteria living in our gut.
Gut Bacteria Step Up
A team of researchers from Cambridge University has found that certain gut bacteria can absorb large amounts of PFAS. In the lab, nine species were able to soak up as much as 75% of the toxic chemicals they were exposed to—some within just minutes. These microbes include familiar names like Bacteroides uniformis, Odoribacter splanchnicus, and Parabacteroides distasonis—species already found in healthy human guts.
Even more impressive, when these bacteria were introduced into mice, they absorbed PFAS from the body and passed them out safely in the animals’ waste. This process appeared to reduce PFAS levels in the body, potentially offering a natural way to filter out these harmful chemicals.
How It Works
PFAS molecules are extremely stable, making them difficult for the body to get rid of. Long-chain versions of these chemicals, such as PFOA and PFNA, can remain in human tissues for years. These forms tend to exit the body through feces rather than urine, making the gut an ideal place to trap them.
Scientists believe that the bacteria aren’t just absorbing PFAS randomly—they’re actively drawing them into clumps inside their cells as a defense mechanism. By bundling the chemicals together, the bacteria may prevent PFAS from damaging their internal systems. This ability could allow them to act as living filters, pulling toxins from the gut before they can spread to other parts of the body.
Testing in the Real World
When mice were colonized with the PFAS-absorbing bacteria, their feces contained more PFAS than those of mice without the bacteria, suggesting successful removal from the body.
The lab tests were promising. When mice were colonized with the PFAS-absorbing bacteria, their feces contained more PFAS than those of mice without the bacteria, suggesting successful removal from the body. Even at low levels of exposure—comparable to what people encounter in everyday life—the bacteria still absorbed a consistent percentage of PFAS.
The potential applications are exciting. Researchers are exploring the possibility of creating probiotic supplements that boost the population of these beneficial microbes in the human gut. Such a supplement could help people detox from PFAS naturally, using microbes already found in many healthy digestive systems.
Questions That Still Need Answers
Despite the positive early results, some say it’s too soon to call this a cure. The bacteria have not yet been tested in humans, and there are many variables to consider. People have different microbiomes depending on their diet, genetics, and overall health. It’s unclear whether the bacteria would behave the same way in every person or if they would maintain their PFAS-clearing abilities over time.
Introducing large numbers of even familiar bacteria into the gut could have side effects. Gut ecosystems are delicate, and disrupting the balance might interfere with digestion, immunity, or medication effectiveness. There’s also the question of what happens to PFAS once they’re absorbed by the bacteria—would they remain safely locked away, or could they somehow be released again?
A Promising but Cautious Path Forward
Medical professionals urge caution. While the idea of using bacteria to fight toxins is exciting, researchers must proceed carefully. Long-term human studies are essential before any new probiotic treatments are approved.
Still, the research is a hopeful sign. It suggests that our gut microbes—often overlooked—could be key players in protecting us from toxic environmental threats. They may not only digest food and support the immune system but also help clear out the very chemicals that modern industry has made nearly impossible to avoid.
As scientists continue to explore this possibility, one thing is clear: the tiny organisms inside us may hold powerful answers to some of today’s biggest health challenges.
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