In recent years, mRNA in lipid nanoparticles (mRNA–LNPs) has emerged as a promising strategy for treating numerous conditions, including COVID-19, various cancers and chronic genetic disorders. To date, this technology has not been successfully used for pancreatic diseases, but that could be about to change. In a paper published in Nature, scientists from China report the development of a new lipid nanoparticle drug-delivery system specifically designed for the pancreas.

Some solid materials can cool down or heat up when pressure is applied or released. This behavior enables cooling and heating technologies that do not rely on climate-damaging refrigerant gases. In practice, however, a major obstacle remains: many materials behave differently during heating and cooling, which makes their response difficult to use reliably in real devices. In a study published in the journal Communications Materials, researchers investigate a solid material known for its exceptionally large cooling/heating response (thermal response) under pressure and ask a simple question: can this response be made more reliable? They show that a very small change in composition leads to a clear improvement and use neutron experiments to explain why this improvement occurs.

Will humanity extend into the far future? It's likely many of us think it should. The problem is that each of us, individually and collectively, act otherwise—we are destroying the environment and climate at every turn. Now a group of scientists is arguing that civilization needs to specifically and systematically study how our species can ensure its survival, even for millions of years, via a new interdisciplinary field they call "Future Dynamics." Their study is published in Habitable Planet.

Cyanobacteria are among the most significant life forms in the history of our planet. As one of the first organisms to produce oxygen through photosynthesis, they shaped early Earth and created the atmosphere in which complex life could develop. A new study, published in Proceedings of the National Academy of Sciences, shows that filamentous cyanobacteria also developed a navigation mechanism to control their movement when gliding across surfaces.

A research team from The Hong Kong University of Science and Technology (HKUST) has developed GrainBot, an AI-enabled toolkit that automatically extracts and quantifies multiple microstructural features from microscopy images. Designed to meet the growing need for data-driven and autonomous research workflows in materials science, the tool provides a systematic method for converting complex image information into quantitative data, thereby accelerating the discovery and development of next-generation materials.

Particles in the atmosphere, known as aerosols, cool the climate by acting as cloud condensation nuclei. The more cloud droplets form around these particles, the less sunlight penetrates a cloud. This cools the climate, although this process is outweighed by the much stronger greenhouse effect.

A research team at The Hong Kong University of Science and Technology (HKUST) has analyzed 40 years of data covering about 1,500 tropical cyclones and discovered that average rain rates surge by more than 20% in the 60 hours before landfall. The study is also the first to clearly identify the physical mechanisms behind this increase, showing that rising humidity over coastal areas and enhanced land-sea frictional contrasts strengthen convection, intensifying rainfall ahead of landfall. The results provide valuable insights for improving coastal disaster preparedness and early-warning systems.

Researchers at the Weill Institute for Cell and Molecular Biology have uncovered new evidence that two major types of gene-controlling DNA sequences, promoters and enhancers, operate with a shared logic and often perform the same jobs. The finding, made possible through a high-throughput assay they developed called QUASARR-seq, could reshape how scientists design gene therapies, interpret disease-related mutations, and understand cancer genetics.

Every year, over 100 billion nitrile rubber gloves are produced. They are made from synthetic polymers—a material chemically related to plastic and derived from crude oil. The vast majority is used in the health care sector, and most are discarded after single use. This creates a massive amount of material waste globally. However, Simon Kildahl, a postdoc at the Department of Chemistry at Aarhus University, has moved a step closer to a way of recycling these gloves. In a new study published in the journal Chem, he and his colleagues demonstrate how they can transform waste rubber into a CO2 adsorbent in the laboratory. The potential, he explains, is significant.

At newly colonized high-elevation sites in the central Italian Apennines, female Daubenton's bats take turns using the same hunting spots instead of feeding side by side. A study published by a research team from the University of Naples Federico II, Museum für Naturkunde Berlin, and several international partner institutions in the journal Global Ecology and Conservation shows that this fine-scale temporal partitioning helps the bats avoid competition and may be crucial for surviving at the cold edge of a climate-driven range expansion.