Scientists at Oregon Health & Science University have uncovered a previously unknown system of internal "trade winds" that help cells rapidly move essential proteins to the front of the cell, reshaping how researchers understand cell migration, cancer spread and wound healing.

In a demonstration that could help pave the way for gene therapies with fewer side effects, several human cell types have been genetically modified with protein nanoparticles designed at University of Michigan Engineering and Michigan Medicine. Gene therapy has been enormously successful for treating disorders of the blood, including sickle cell disease and leukemia. However, using a virus as a vector for treatment can create unwanted side effects, such as secondary cancers and immune system overreactions. With the nanoparticles, the research team aims to develop a safer method for delivering gene therapies.

In chemical processes for producing pharmaceuticals, catalysts are a core technology that determines production speed and cost. However, until now, there has been a trade-off between "precise but disposable catalysts" and "reusable catalysts." A KAIST research team has developed an eco-friendly catalytic technology that combines these two types, operating solely with light and air. This opens a pathway to producing pharmaceutical ingredients more cheaply and cleanly, with expected reductions in carbon emissions and environmental pollution. The study is published in the Journal of the American Chemical Society.

Bacteria are a major cause of infections and death in hospital settings, due—in part—to the rising incidence of antibiotic resistance. In the United States, antibiotic-resistant bacteria are involved in more than 2 million infections and cause 23,000 deaths annually. There's a growing need for new options that can both treat infections and limit resistance.

Scientists in the Riccio College of Engineering at the University of Massachusetts Amherst and the University of California Santa Barbara have demonstrated key laser and ion trap components necessary to help drastically shrink the size of quantum computers, an achievement aligned with the shrinking of integrated microprocessors in the 1970s, 80s and 90s that allowed computers to move from room-sized behemoths to today's ultrathin smartphones.

Is your houseplant thirsty? Are crops getting enough water? Is a forest at high risk of wildfire? Leaf health can answer all these questions, and researchers at The University of Texas at Austin have developed new technology to measure hydration levels with greater accuracy and without hurting the plant. The researchers developed an electronic tattoo for leaves that uses the hyperflexible and sustainable material graphene to track hydration levels. It sticks on the leaves without harming them, a major improvement over current methods that work only with dead or dried-out leaves or provide indirect measurements.

A team at Helmholtz Munich and the Technical University of Munich (TUM) has developed a new microscopy technique that can distinguish lipid species in living cells—in particular cholesterol and sphingomyelin—and map them without the need for chemical labeling. By combining mid-infrared illumination with optoacoustic detection, the method reads the lipids' natural spectral fingerprints, eliminating the need for specific fluorescent tags, which are laborious to develop and may interfere with lipid function. The team published its results in the journal Nature Methods.

Researchers at the University of Bayreuth have, for the first time, deciphered key steps in the biosynthetic mechanism of the potential anti-cancer agent fostriecin. The team led by Prof. Dr. Frank Hahn has succeeded in producing all enzymes involved in the process in the laboratory and examining them individually under controlled conditions. In the long term, the findings may pave the way for more efficient production of the compound and open up new avenues in cancer therapy. The researchers have published their findings in Nature Communications.

A research team led by Professor Jiwoong Yang of the Department of Energy Science and Engineering at DGIST has developed next-generation optical sensor technology capable of precisely detecting not only the intensity and wavelength of light but also its rotational direction—the spin information of photons. The team successfully implemented a quantum-dot-based optical sensor that can detect circularly polarized light (CPL) across an ultra-wide spectral range—from ultraviolet to short-wave infrared—demonstrating photodetection performance comparable to that of commercial silicon optical sensors. The paper is published in Advanced Materials.

In physics, some waves behave in a surprising way: instead of spreading out and fading, they hold their shape as they travel at constant speeds. These unusual waves, called solitons, have interested scientists since they were first observed in canals in the 19th century. Today, researchers study solitons in everything from optical fibers to biological systems.