If you've been holding on to your smartphone for quite some time and are confused about whether it's time to upgrade, here are some signs to look for.

When a cell receives a message from outside, it generates a molecule called cyclic AMP (cAMP) to relay this message. To ensure the signal reaches the correct effector without triggering pathways accidentally, cAMP levels must be maintained around their point of origin and at the right level. ABCC4, a protein that transports cAMP out of cells and also contributes to drug resistance, helps with this local control. Yet, how ABCC4 is held in place at the right spot to perform these functions was not clear.

Japan reportedly is pressing the Trump administration to more forcefully defend Prime Minister Sanae Takaichi after her warning that a Chinese attack on Taiwan could become an "existential threat" to Japan set off furious reactions from Beijing.

Treasury Secretary Scott Bessent said Sunday the U.S. is having a "very strong holiday season," noting that consumer spending has held up "across the income cohort.""There is nothing to say that there are two dolls instead of 30 dolls," Bessent said on CBS's "Face the...

The U.S. Department of Transportation is waiving part of a fine assessed against Southwest Airlines after the company canceled thousands of flights during a winter storm in 2022.Under a 2023 settlement reached by the Biden administration, Southwest agreed to a $140 million...

Secretary of War Pete Hegseth gives a speech at the Reagan National Defense Forum at the Ronald Reagan Presidential Library in Simi Valley, Calif., on Dec. 6, 2025. Caylo Seals/Getty ImagesSIMI VALLEY,…

Federal immigration agents under the Trump Administration have rescued more than 62,000 migrant children from situations involving sex trafficking and forced labor, White House border czar Tom Homan announced…

The Department of Justice is looking at gun rights as civil rights for a change. This is incredibly good news because, well, gun rights are civil rights. They're part of the Bill of Rights for a reason,…

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