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Science Explorer
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Escaping the endosome: BEND lipids improve LNP mRNA delivery and gene editing
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Escaping the endosome: BEND lipids improve LNP mRNA delivery and gene editing

Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking system and its counterpart on the station. Thanks to international standards, these mechanisms are universally compatible, ensuring astronauts and cargo can safely and seamlessly enter the station.
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Mouse with two fathers survives to adulthood, marking scientific milestone
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Mouse with two fathers survives to adulthood, marking scientific milestone

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse—a mouse with two male parents—that lived until adulthood.
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Novel enzyme profiling method identifies top candidates for plastic recycling
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Novel enzyme profiling method identifies top candidates for plastic recycling

Polyethylene terephthalate (PET) is one of the most widely used plastics, commonly found in bottles, fibers, and many other products. It is a unique member of the plastic family as it can be broken down into its constituent units (or monomers) by PETases, which are enzymes that degrade PET. Until now, scientists have discovered a variety of PETases in nature, including from bacteria, Ideonella sakaiensis, and leaf-compost cutinase. These biocatalysts have been modified for industrial applications.
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How a multitasking protein keeps the body's clock in sync
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How a multitasking protein keeps the body's clock in sync

If your genes could set an alarm clock, EZH1 might be the one ringing the bell. A new study has revealed how this underappreciated protein ensures the rhythmic expression of genes in skeletal muscle, aligning them with the body's 24-hour internal cycles. The findings are published in The EMBO Journal.
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Peculiar icy objects in outer reaches of the Milky Way perplex astronomers
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Peculiar icy objects in outer reaches of the Milky Way perplex astronomers

A trio of astronomers from the University of Tokyo and Niigata University have found what they describe as "peculiar embedded icy objects" thousands of light years from Earth. Takashi Shimonishi, Itsuki Sakon and Takashi Onaka have posted a paper describing their discoveries and offering possible ideas regarding their nature on the arXiv preprint server.
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An overlooked nuclear force helps keep matter stable, study reveals
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An overlooked nuclear force helps keep matter stable, study reveals

Researchers from Kyushu University, Japan have revealed how a special type of force within an atom's nucleus, known as the three-nucleon force, impacts nuclear stability. The study, published in Physics Letters B, provides insight into why certain nuclei are more stable than others and may help explain astrophysical processes, such as the formation of heavy elements within stars.
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Large magma bodies found beneath dormant volcanoes, surprising scientists
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Large magma bodies found beneath dormant volcanoes, surprising scientists

New Cornell University led-research challenges the long-standing belief that active volcanoes have large magma bodies that are expelled during eruptions and then dissipate over time as the volcanoes become dormant.
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'Doomsday Clock' moves closer to midnight amid threats of climate change, nuclear war, pandemics, AI
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'Doomsday Clock' moves closer to midnight amid threats of climate change, nuclear war, pandemics, AI

Earth is moving closer to destruction, a science-oriented advocacy group said Tuesday as it advanced its famous "Doomsday Clock" to 89 seconds till midnight, the closest it has ever been.
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Scientists create 'molecular trap' to remove pollutants from water
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Scientists create 'molecular trap' to remove pollutants from water

Scientists from The University of Manchester have developed a new material that could help reduce water pollution caused by harmful chemicals, such as from leftover medicines and hygiene products, that end up in rivers and lakes.
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Juno mission spots most powerful volcanic activity on Io to date
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Juno mission spots most powerful volcanic activity on Io to date

Even by the standards of Io, the most volcanic celestial body in the solar system, recent events observed on the Jovian moon are extreme.
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