Part of why so many fans view actress Jennifer Lawrence as such a beloved talent is her ability to get real and very, very raw. She has never shied away from roles that begged her to strip down emotionally and bare everything. In one of her breakthrough roles in the film Winter's Bone, she plays a teenager who must fend for her family in the face of homelessness. In Silver Linings Playbook, she won a Best Actress Oscar for her daring role as a charming woman with mental health issues.Language might not be suitable for a younger readers. - YouTube, Silver Linings Playbook, Jennifer Lawrence, Bradley Cooper www.youtube.com She just seems to have a way of adding a bit of "charm-dust" to every part, whether it's action-driven, serious drama, or something in between. In her latest film, Die, My Love, (described as a comedy/horror) she plays a woman suffering from postpartum depression and psychosis as she watches her marriage dissolve. Based on the novel by Ariana Harwicz, this film adaptation is written and directed by Lynne Ramsay, who is known to push uncomfortable boundaries in her movies. The film, co-produced by Martin Scorsese, received a six minute standing ovation upon its premiere. At Cannes, Jennifer gave an unexpectedly candid interview at a press conference. She admits she isn't usually an actress who "takes her work home," but in this case, as a mother with one on the way during filming, she knew all too well about mental health issues that often come with post-pregnancy. When discussing her character in the film, she shares, "Yes, a part of what she's going through is the hormonal imbalance that comes with postpartum. But she's also having an identity crisis." See on Instagram Her eyes begin getting wet as she asks, "'Who am I as a mother? Who am I as a wife? Who am I as a sexual person to my husband? Who am I as a creative?"She vulnerably adds, "And I think she's plagued with this feeling that she's disappearing. So for me, I was four and a half, five months pregnant when we shot. Great hormones, feeling great—which is really kind of the only way I was able to dip into this visceral emotion."She adds a nod to her writer and director, saying, "Also, in terms of answering any question about my acting or performance at all, I have Lynne Ramsay as my director, so that's kind of it."The comment section of the Deadline Instagram reel was bright with support for both the film and Jennifer herself. Comedian Chelsea Handler topped the section by writing, "Love everything Jen says and does." Another person wrote, "She's so real," with one more adding, "She just described every new mother."One commenter notes, "She's a mom. She's gonna make it personal. I hope she stays true to her own motherhood."To that point, in a different clip from the same press conference posted on YouTube by Page Six, Jennifer goes into detail about what having children feels like to her. "It changes everything. It's brutal and incredible. I didn't know I could feel so much, and my job has a lot to do with emotion. They've opened up the world to me. It's almost like feeling like a blister or something—so sensitive. So they've changed my life, obviously for the best, and they've changed me creatively." Jennifer Lawrence in a press conference at Cannes Film Festival www.youtube.com, Page Six In terms of how being a new mom affected her role, she says, "Obviously, as a mother, it was really kind of hard to kind of separate what 'I would do' as opposed to what she would do. And it was just heartbreaking. When I first read the book… I had just had my firstborn. And there's not anything like postpartum. It's extremely isolating… The truth is, extreme anxiety and extreme depression is isolating, no matter where you are. You feel like an alien, and it so deeply moved me."

One little girl is somersaulting her way into people’s hearts, and reminding us all of how important it is to put yourself out there every once in a while. In a now-viral TikTok clip posted by @ashleydkennedy14, we learn that her kindergarten-aged niece had apparently entered herself into a talent show without telling her mom—a feat that involved forging mom’s signature onto a permission slip, no less. And just what did this “act” consist of? Somersaults. Lots of ‘em. Six, to be exact. Also one cartwheel, for good measure. She’d basically deliver one roll, wait for uproarious applause, then do another one. Solid routine, if you ask us. Honestly, it’s hard to tell which aspect of this moment is more endearing: watching this little girl valiantly overcome a wee bit of shyness—and in the process tapping into some pretty captivating stage presence—or seeing how enthusiastic the audience was to support her. Just good, wholesome stuff all around. Watch: @ashleydkennedy14 lol. I’m ☠️☠️. She signed the form herself. #fyp #lol #funny #talentotiktok ♬ Get Ready - Steve Aoki Vocal Radio Edit - 2 Unlimited Even online viewers were taken aback by this girl’s fearlessness. Or rather, her determination to keep going, in spite of her fear.“I need to know what her parents did because this is CEO level confidence and I am here for it.”“She was like oh ? u like that ?” Nailed it. media4.giphy.com “Im honestly impressed by her independence. She signed herself up and was confident that she had it. Good job mama.” “She will go far in life. Courage is everything.” Others noted how kind the crowd was to cheer her on. “For the people who clapped, as a mother: THANK YOU. it means a lottt.” “The cheers from the crowd are the best.” “Ok. because the crowd passed the vibe check. We cheer over here, be brave!”Funnily enough, plenty of other folks chimed in with similar stories of kiddos sneaking into talent shows…with talents they may or may not have actually possessed. “My son tried to sign himself up to do karate at his school talent show…he’s never been to a karate class in his life…” Watch out, she knows karate! media1.giphy.com “My daughter entered herself into the talent show in 1st grade and didn’t say anything. She played the piano… she had never played piano in her life til that day lol I need that confidence.” “My brother did this! He played harmonica for the whole school. He doesn’t know how to play the harmonica.” While this girl might receive a stern talking to about the importance of not forging signatures, her story is nonetheless a prime example of how kids can really shine when left on their own to take risks, try new things, and opt for exploration over perfection. It can be hard for parents to not want to protect their little ones from failure (whatever that means), but life often provides moments just like this to remind them that taking a step back is a precious opportunity to help instill some self advocacy. It’s just like the old saying goes, “Leap, and the net will appear.” Or in this case…somersault, and the cheers will follow.

If an orange cat were to show up at your doorstep and you had to wager whether it was male or female, the odds would definitely be in your favor if you bet male. Only around 20% of orange cats are female, making them fairly rare (though not as rare as a male calico cat, as 99.9% of calicos are female). Up until now, scientists assumed that the male-to-female ratio for orange cats was due to an X chromosome gene mutation. Since male cats have XY chromosomes, having the gene mutation on the X chromosome makes a male cat orange. But since female cats have two X chromosomes, they have to inherit the mutation on both of them, making it statistically less likely for a female cat to come out with orange fur. While the fact that a sex-linked gene causes orange coloring in cats was understood, which specific gene and what kind of mutation have been an elusive mysteries for decades. A genetic mutation deletes a piece of DNA that usually suppresses a specific gene in orange cats.Photo credit: CanvaNot anymore. In two studies published simultaneously in the journal Current Biology in May 2025, geneticists at Stanford University in the U.S. and Kyushu University in Japan have pinpointed the exact gene mutation that causes orange pigmentation in cats. The gene is known as Arghap36, and the mutation appears to delete a section of DNA that normally suppresses the expression of the gene, allowing it to remain active. But the finding was surprising in a few ways.“At the time we found it, the Arhgap36 gene had no connection to pigmentation,” said Stanford geneticist and lead author Christopher Kaelin, PhD. in a statement. Arhgap36, which has been studied in cancer and developmental biology research, is normally expressed in neuroendocrine tissues. Overexpression there can lead to tumors, but the increased activity of the gene in orange cats causes their unique pigmentation. Most orange cats are male. Giphy by UC Davis “In a number of species that have yellow or orange pigment, those mutations almost exclusively occur in one of two genes, and neither of those genes are sex-linked,” Kaelin said. “The mutation in orange cats seems to turn on Arghap36 expression in a cell type, the pigment cell, where it’s not normally expressed.”Notably, this seems to truly be specific to orange cats and only orange cats.“Arghap36 is not expressed in mouse pigment cells, in human pigment cells or in cat pigment cells from non-orange cats,” Kaelin said. “The mutation in orange cats seems to turn on Arghap36 expression in a cell type, the pigment cell, where it’s not normally expressed. Certainly, this is a very unusual mechanism where you get misexpression of a gene in a specific cell type." Orange cat pigmentation is due to a unique gene mutation. Photo credit: CanvaThe development of genomic research over the past five to ten years is what enabled the scientists to pinpoint the way the gene mutation works. Hiroyuki Sasaki, a self-proclaimed cat-lover and geneticist at Kyushu University’s Medical Institute of Bioregulation and the Institute for Advanced Study, organized a crowdfunded effort in Japan, raising $70,000 so he could fund his study.“Identifying the gene has been a longtime dream, so it’s a joy to have finally cracked it,” Sasaki said in a statement. "Arghap36 is essential for development, with many other roles in the body, so I had never imagined it could be the orange gene."Sasaki points out that the DNA deletion lies in a non-coding deletion region of the gene, so the protein itself doesn't change. Arghap36 is also active in many areas of the body, including the brain and hormonal glands, which means the activation of it could theoretically affect more than just fur color in orange cats. — (@) “For example, many cat owners swear by the idea that different coat colors and patterns are linked with different personalities,” laughs Sasaki. “There’s no scientific evidence for this yet, but it’s an intriguing idea and one I’d love to explore further.”One thing the scientists don't know for sure is when along the line of evolution this mutation first occurred. Kaelin says it probably occurred early in the domestication process, but Sasaki has ideas for figuring it out.“One idea is to study ancient Egyptian cat paintings—or even to test DNA from mummified cats—to see if any cats back then were orange,” he says. “It’s ambitious, but I’m excited to try.”You can read more about the study from Stanford University here and the Kyushu University study here.