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1 h

Decoded rules of microRNA strand selection reveal conserved, programmable features

Decoded rules of microRNA strand selection reveal conserved, programmable features

MicroRNAs, whose discovery was recognized with the 2025 Nobel Prize in Physiology or Medicine, are central regulators of gene expression, yet a fundamental question has remained unanswered: how cells choose between the two strands produced from each microRNA precursor.

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1 h

A new 'crystalline sponge' for drug discovery: APF-80 illuminates materials design

A new 'crystalline sponge' for drug discovery: APF-80 illuminates materials design

Many natural compounds that act on the human body provide active ingredients for medicines or clues for developing them, and they play a crucial role in pharmaceutical research.

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1 h

Health care electronics are booming—here's how to make them more sustainable

Health care electronics are booming—here's how to make them more sustainable

Wearable health care devices—such as glucose monitors, ultrasound patches and blood-pressure monitors—can be invaluable for keeping patients safe.

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1 h

Two-step genome editing enables creation of full-length humanized mouse models

Two-step genome editing enables creation of full-length humanized mouse models

Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory landscapes often diverge, limiting how accurately mouse models can mimic human biology.

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1 h

Study finds albumin, the most abundant blood protein, acts as a shield against deadly fungal infections

Study finds albumin, the most abundant blood protein, acts as a shield against deadly fungal infections

Scientists at the Institute of Molecular Biology and Biotechnology (IMBB-FORTH) and the University of Crete, together with collaborators from Greece, Europe, the U.S., and India, have discovered a novel role of albumin, the most abundant protein in human blood, in protecting against a rare and often deadly fungal infection called mucormycosis. The study is published in Nature.

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1 h

AI tools speed development of antibody probes to see activity inside living cells

AI tools speed development of antibody probes to see activity inside living cells

Researchers at Colorado State University have determined how to use artificial intelligence to modify antibodies so they act as lightbulbs, enabling scientists to better see inside living cells to track errors in gene expression that can lead to cancer and other disorders.

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1 h

Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging

Tightening the focus of subcellular snapshots: Combined approach yields better cell slices for cryoET imaging

Taking images of tiny structures within cells is tricky business. One technique, cryogenic electron tomography (cryoET), shoots electrons through a frozen sample. The images formed by the electrons that emerge allow researchers to reconstruct the internal architecture of a cell in 3D with near-atomic resolution.

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1 h

Living together with differences: Mathematical model shows how to reduce social friction without forcing consensus

Living together with differences: Mathematical model shows how to reduce social friction without forcing consensus

Opinion polarization is often considered as the primary driver of social friction, leading to exhaustive efforts to force a consensus. However, new research suggests a more pragmatic goal: reducing the friction of disagreement without necessarily eliminating the diversity of opinion.

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1 h

Mysterious iron 'bar' discovered in famous nebula

Mysterious iron 'bar' discovered in famous nebula

A mysterious bar-shaped cloud of iron has been discovered inside the iconic Ring Nebula by a European team led by astronomers at University College London (UCL) and Cardiff University.

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1 h

How a respiratory bacterium obtains essential lipids from the human body and targets fat-rich tissues

How a respiratory bacterium obtains essential lipids from the human body and targets fat-rich tissues

A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae—responsible for atypical pneumonia and other respiratory infections—to obtain cholesterol and other essential lipids directly from the human body.

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